Our Technology

Cloud-based Infrastructure

The Cerora Borealis multimodal biosensor solution combines single lead EEG brainwave sensor data (1) that is wirelessly transmitted to a tablet or laptop. EEG sensor data is combined with other modalities of neurological assessment data (2-6). Together these data are transmitted in a HIPAA compliant manner to Cerora’s cloud infrastructure. In the cloud, these data are analyzed using custom and proprietary algorithms to generate clinical reports in about 1 minute. The reports can then be sent to telehealth physicians for interpretation and then provided to trainers, nurses, and other field clinicians to assist in the identification and management of concussion, for instance making ‘Return-to-Learn’ and ‘Return-to-Play’ decisions.

Electroencephalography (EEG)

Electroencephalography (EEG) is the measure of the electrical activity that your brain generates. When brain cells, or neurons, communicate with one another, voltages are produced by the movement of ions in and out of neurons. This is similar to the electrical activity of your heart. However, neurons in the brain are frequently activated in large groups and at different frequencies. The synchronous activity of these large groups of neurons generate ‘brainwaves’ that are recorded on the scalp during an EEG. Brainwaves can change for a number of reasons including when a person gets drowsy, falls asleep, is resting, in deep thought, or for pathologic reasons including after a concussion.

For more information please see this scholarpedia article.

At Cerora, we believe that a measure of brainwaves with objective biosensors will be an essential component of a multimodal assessment of brain health.

Cognitive Testing

Computer-Based Neuropsychological Testing

A number of neuropsychological tests, including reaction time tests, are well validated measures to assess multiple cognitive domains of a person, including memory, neuro-ocular motor function, and speech. Building on this clinical literature, Cerora’s platform includes a number of these tasks like reaction time tests and immediate word recall tests and novel computer-based neuropsychological tasks like an improved neuro-ophthalmological saccade task that involves prefrontal cortex functions including working memory. Cerora will be submitting Borealis for review by FDA and other applicable regulatory authorities. When cleared or approved for marketing, Borealis will include similar neurological assessment tasks in combination with objective biosensor-based measurements.

Subjective Psychological Assessment

Self-reported psychological impressions are subjective, but remain at the core of clinical assessment tools for diagnosing brain-related injury and cognitive disorders. The Cerora platform includes a number of validated symptom checklists to aid in assessing the status of brain-health in school-age children, adults, and seniors. Cerora will be submitting Borealis for review by FDA and other applicable regulatory authorities. When cleared or approved for marketing, Borealis will include self-report inventories in combination with objective biosensor measurements.